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Figure 1 | BMC Systems Biology

Figure 1

From: Autocrine FGF feedback can establish distinct states of Nanog expression in pluripotent stem cells: a computational analysis

Figure 1

Suggested interactions of the NANOG-OCT4-SOX2 core module of transcriptional embryonic stem cell regulation. Black, green, red and blue arrows represent complex formation, transcriptional activation, repression and translation, respectively. a: The symmetric model considered by Chickarmane et al. [8]. b: The model suggested by Pan et al. [5] includes negative feedbacks through OCT4. c: The NANOG autoinhibitory circuit suggested by Navarro et al. [10].

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