Figure 4
Scheme of a bifurcation diagram for a bistable reaction network and its corresponding forward and backward dose response curves. A) Bifurcation diagram where the x-axis is the total concentration of a particular moiety and the y-axis is the concentration of a given species. Stars indicate tangent bifurcations also known as saddle nodes or limit points (LP). Unstable equilibria lie on the dashed curve. B) Corresponding forward dose response curve. C) Corresponding backward dose response curve.