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Table 2 Viable parameter regions for the protein activation network and Monte Carlo confidence intervals

From: A method for inverse bifurcation of biochemical switches: inferring parameters from dose response curves

Parameter

Equivalence

Lower bound

Upper bound

Monte Carlo confidence interval

 

ρ 1

k 14/k 41

0.0028

0.0174

(0.0029, 0.0108)

 

ρ 2

k 18

65.0697

530.5599

(131.4882, 275.2975)

 

ρ 3

k 26/k 62

0.4873

1.2835

(0.5230, 1.4477)

 

ρ 4

k 37/k 73

0.0652

0.0699

(0.0644, 0.06919)

 

ρ 5

k 57

0.0160

0.0175

(0.0161, 0.0179)

 

ρ 6

α l

-0.2403

-0.2224

(-0.2446, -0.2263)

 

ρ 7

α u

-0.1424

-0.1297

(-0.1469, -0.1303)

 
  1. k 14 and k 37 were fixed at 1 and 0.01 respectively.