Table 2 Hub proteins identified in the zebrafish intracellular PPI network for secondary infection
Rank | Zebrafish protein | Degree | GO functional annotation |
|---|---|---|---|
1 | Psmd1 | 16 | Antigen processing and presentation of exogenous peptide antigen via MHC class I |
2 | Fos | 12 | Innate immune response |
3 | Psmd13 | 11 | Antigen processing and presentation of exogenous peptide antigen via MHC class I |
4 | Ndrg1 | 10 | Mast cell activation |
5 | Casp2 | 10 | Regulation of apoptosis |
6 | Gch2 | 10 | Response to interferon-γ |
7 | Ncstn | 9 | T cell proliferation |
8 | Acvr1b | 9 | TGF-β receptor activity |
9 | Uba5 | 9 | Protein ubiquitination |
10 | Usp14 | 8 | Regulation of proteasomal protein catabolic process |