Figure 4
From: A curated C. difficile strain 630 metabolic network: prediction of essential targets and inhibitors
Flow chart representing the main steps of reconstruction of a metabolic network. The creation of the network begins by the building of a draft by extracting data from various databases. The draft will then enter an iterative cycle between curation and validation, each steps of validation bringing a new step of curation if it fails. The final version of the network can then be used to perform various analyses (growth tests, in silico gene deletion, etc.).