TY - JOUR AU - Plaisier, Christopher L. AU - Lo, Fang-Yin AU - Ashworth, Justin AU - Brooks, Aaron N. AU - Beer, Karlyn D. AU - Kaur, Amardeep AU - Pan, Min AU - Reiss, David J. AU - Facciotti, Marc T. AU - Baliga, Nitin S. PY - 2014 DA - 2014/11/14 TI - Evolution of context dependent regulation by expansion of feast/famine regulatory proteins JO - BMC Systems Biology SP - 122 VL - 8 IS - 1 AB - Expansion of transcription factors is believed to have played a crucial role in evolution of all organisms by enabling them to deal with dynamic environments and colonize new environments. We investigated how the expansion of the Feast/Famine Regulatory Protein (FFRP) or Lrp-like proteins into an eight-member family in Halobacterium salinarum NRC-1 has aided in niche-adaptation of this archaeon to a complex and dynamically changing hypersaline environment. SN - 1752-0509 UR - https://doi.org/10.1186/s12918-014-0122-2 DO - 10.1186/s12918-014-0122-2 ID - Plaisier2014 ER -