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Figure 3 | BMC Systems Biology

Figure 3

From: CBFA: phenotype prediction integrating metabolic models with constraints derived from experimental data

Figure 3

Screenshots of CBFA: a) Load model – the first step is to load a metabolic model and a new project will be created and made available on the clipboard of the application. Afterwards, it is possible to visualize their information through the available views; b) Configure constraints – different type of constraints can be configured through the use of graphical interfaces that enable to set the parameters to create the datatypes to be used on further operations; c) Perform flux analysis/knockout flux analysis – the user can select different constraints to perform several flux analysis methods using a metabolic model. It is also possible to configure a set of knockouts and perform flux analysis over the mutant with the same constraints; d) Visualization – the results of the operations create/update datatypes on the clipboard, and the output can always be checked through the views that are defined for the datatypes.

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