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Figure 4 | BMC Systems Biology

Figure 4

From: Space-induced bifurcation in repression-based transcriptional circuits

Figure 4

The switch from oscillations to stationarity as a demixing-induced bifurcation of the segregated configuration (2D simulations). The average value of the first zero crossing of the ACF (FZCA) is reported as a function of the degree of demixing r/R, for uniform (black line), clustered (brown circles) or segregated (magenta circles) gene configurations. For each value of r/R and each gene configuration, 20 simulations were run (with different realizations of the random choices). Circles (or full horizontal lines) are the average of the 20 resulting FZCA while bars (or dashed horizontal lines) show ± 1 s.d. Labels (a), (b) and (c) locate the parameters used to generate the corresponding subpanels of Figure 3. Size of the spatial domain R=400, G T =5 copies. All other parameters were according to the standard set defined in the Methods section.

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