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Table 2 Comparison of CPU times for the branched pathway case study

From: Parameter estimation of dynamic biological network models using integrated fluxes

CPU time a(sec)

Noise-free data b

Noisy data c

 

(s,o)=(3,3)

(s,o)=(5,3)

(s,o)=(3,5)

(s,o)=(3,3)

(s,o)=(5,3)

(s,o)=(3,5)

SPE-slope

933.84

1255.4

1182.6

207.7 ± 149.3

111.2 ± 70.5

40.2 ± 13.8

IPE-slope

106.48

104.55

185.38

96.8 ± 17.1

105.4 ± 16.0

102.9 ± 36.5

IPE-ODE

415.32

1380.1

1018.9

433.9 ± 70.6

456.4 ± 141.9

469.3 ± 174.4

SPE-ODE

14.8 hours d

9002 ± 4839

IFPE

1263

655.9 ± 198.5

IFPE-ODE

2154

1023 ± 315

  1. aThe CPU times were recorded using a workstation with Intel Xeon processor 3.33 GHz with 18 GB RAM.
  2. bFor noise-free data, five independent runs were carried out. The CPU time is reported for the run with the lowest objective function value.
  3. cFor noisy data, the reported values are the mean ± standard deviation of five technical replicates of the data.
  4. dOnly three our of five repeated runs finished within 24 hours. The CPU time corresponds to the run with the lowest objective function value among the three successful runs.
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BMC Systems Biology

ISSN: 1752-0509

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