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Figure 4 | BMC Systems Biology

Figure 4

From: Spatial localization of the first and last enzymes effectively connects active metabolic pathways in bacteria

Figure 4

Localization dynamics of cell wall synthesis enzymes. A. Red arrow indicates a cell where MurA-CFP (left) and MurG-GFP (middle) colocalize as shown in the overlaid image (right) together with membrane dye (red). B. Model for organization of enzymes from the cell wall synthesis pathway going from a diffuse localization during stationary growth to a discrete concentration of MurA and MurG during exponential growth. C. Left images, Timecourse distribution of enzyme MurA-CFP in B.subtilis during exponential and stationary growth. Right graph, percentage of cells showing over time localized MurA-CFP (blue, right axis) compared to the culture optical density (black, left axis).

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