Spatial localization of the first and last enzymes effectively connects active metabolic pathways in bacteria

BMC Systems Biology

Table 1 Table of enriched gene ontology categories

Gene ontology enrichment analysis	Enzymes	Localized enzymes	Expected	P-values fisher’s exact test
Nucleotide binding	438	46	25	2.11E-05
Manganese ion binding	70	14	4	3.08E-05
Magnesium ion binding	170	23	10	8.06E-05
ATP binding	427	43	25	1.15E-04
Ubiquinone synthesis	18	6	1	3.49E-04
Amino acid binding	18	6	1	3.49E-04
5′-nucleotidase activity	4	3	0.2	7.19E-04
Chemotaxis	22	6	1.3	1.16E-03
L-lyxose metabolism	5	3	0.3	1.72E-03
Lyase activity	80	12	4.6	1.79E-03
Fatty acid biosynthesis	17	5	1	2.10E-03

Table of enriched GO categories for E.coli enzymes showing GFP localization under exponential growth. First column shows the category, second column the number of enzymes in that category, third column the number of enzymes from the list of 219 localized ones that are in the category, fourth column is the number of enzymes in the category expected by chance and the fifth column is the p-value calculated as the Fisher exact test.

ISSN: 1752-0509