From: Dynamic estimation of specific fluxes in metabolic networks using non-linear dynamic optimization
Choice of K | Knot intervals for free flux | SSE | AIC | n p | ||
---|---|---|---|---|---|---|
 | 1 | 2 | 3 |  |  |  |
1, 4 and 5 | 7, 9, 10, 11 | — | 8, 12 | 7.49 | 79.9 | 25 |
3, 6 and 7 | 10, 11, 12 | 10, 11, 12 | 7, 8, 10, 11 | 49.50 | 160.4 | 33 |
Orthonormal | 8, 11, 12 | 9, 10, 11 | 7, 8, 10, 11 | 14.41 | 125.3 | 33 |
Optimal | 7, 9, 10, 11 | — | 8, 12 | 1.33 | 86.9 | 28 |