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Table 2 48 tumor suppressors and oncogenes from TCGA data

From: Integrative network analysis of TCGA data for ovarian cancer

Oncogene/suppressor

Gene symbol

Name

Suppressor

CDKN2A

Cyclin-Dependent Kinase Inhibitor 2A

Suppressor

MAP2K4

Mitogen-Activated Protein Kinase Kinase 4

Suppressor

MAGEC1

Melanoma Antigen Family C, 1

Suppressor

RIMBP2

RIMS Binding Protein 2

Suppressor

DIRAS3

DIRAS Family, GTP-Binding RAS-Like 3

Suppressor

PEG3

Paternally Expressed 3

Suppressor

DAB2

Disabled Homolog 2, Mitogen-Responsive Phosphoprotein

Suppressor

NF1

Neurofibromin 1

Suppressor

ARID1A

AT Rich Interactive Domain 1A

Suppressor

OPCML

Opioid Binding Protein/Cell Adhesion

Suppressor

PLAGL1

Pleiomorphic Adenoma Gene-Like 1

Suppressor

CASP9

Caspase 9, Apoptosis-Related Cysteine Peptidase

Suppressor

WWOX

WW Domain Containing Oxidoreductase

Suppressor

RPS6KA2

Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2

Suppressor

SPARC

Secreted Protein, Acidic, Cysteine-Rich

Suppressor

DLEC1

Deleted In Lung And Esophageal Cancer 1

Oncogene

THY1

Thy-1 Cell Surface Antigen

Oncogene

ALG3

Alpha-1, 3-Mannosyltransferase

Oncogene

ATP5E

ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, Epsilon Subunit

Oncogene

ATP6V1C1

ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1

Oncogene

C19orf53

Chromosome 19 Open Reading Frame 53

Oncogene

CSNK2A1

Casein Kinase 2, Alpha 1 Polypeptide

Oncogene

CTSF1

Cathepsin F

Oncogene

DERL1

Derlin 1

Oncogene

HSF1

Heat Shock Transcription Factor 1

Oncogene

ITPA

Inosine Triphosphatase

Oncogene

MRPL34

Mitochondrial Ribosomal Protein L34

Oncogene

NCBP2

Nuclear Cap Binding Protein Subunit 2

Oncogene

NDUFA13

NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 13

Oncogene

NDUFB7

NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 7

Oncogene

NDUFB9

NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 9

Oncogene

OSBPL2

Oxysterol Binding Protein-Like 2

Oncogene

POLR2H

Polymerase (RNA) II (DNA Directed) Polypeptide H

Oncogene

PIK3R1

Phosphoinositide-3-Kinase, Regulatory Subunit 1

Oncogene

AKT2

V-Akt Murine Thymoma Viral Oncogene Homolog 2

Oncogene

ERG

V-Ets Erythroblastosis Virus E26 Oncogene Homolog

Oncogene

PTK2

Protein Tyrosine Kinase 2

Oncogene

RAE1

RAE1 RNA Export 1 Homolog

Oncogene

RIOK1

RIO Kinase 1

Oncogene

SNRPB2

Small Nuclear Ribonucleoprotein Polypeptide B

Oncogene

SNX5

Sorting Nexin 5

Oncogene

SRXN1

Sulfiredoxin 1

Oncogene

STX10

Syntaxin 10

Oncogene

TRMT1

TRNA Methyltransferase 1 Homolog

Oncogene

TRMT6

TRNA Methyltransferase 6 Homolog

Oncogene

WDR53

WD Repeat Domain 53

Oncogene

YWHAZ

Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Zeta Polypeptide

Oncogene

RAB25

RAB25, Member RAS Oncogene Family

  1. Presented in the table are the symbol and name of 48 tumor suppressors and oncogenes identified from TCGA data.