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Table 3 36 tumor suppressors and oncogenes from literature

From: Integrative network analysis of TCGA data for ovarian cancer

Oncogene/suppressor

Gene symbol

Name

Suppressor

RB1

Retinoblastoma 1

Suppressor

PTEN

Phosphatase And Tensin Homolog

Suppressor

DAB2

Disabled Homolog 2, Mitogen-Responsive Phosphoprotein

Suppressor

DLEC1

Deleted In Lung And Esophageal Cancer 1

Suppressor

TP53

Tumor Protein P53

Suppressor

NF1

Neurofibromin 1

Suppressor

SPARC

Secreted Protein, Acidic, Cysteine-Rich

Suppressor

TMPRSS2

Transmembrane Protease, Serine 2

Suppressor

CASP9

Caspase 9, Apoptosis-Related Cysteine Peptidase

Suppressor

PLAGL1

Pleiomorphic Adenoma Gene-Like 1

Suppressor

WWOX

WW Domain Containing Oxidoreductase

Suppressor

RPS6KA2

Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2

Suppressor

BRCA1

Breast Cancer 1, Early Onset

Suppressor

BRCA2

Breast Cancer 2, Early Onset

Suppressor

DIRAS3

DIRAS Family, GTP-Binding RAS-Like 3

Suppressor

PEG3

Paternally Expressed 3

Suppressor

ARID1A

AT Rich Interactive Domain 1A

Suppressor

OPCML

Opioid Binding Protein/Cell Adhesion

Oncogene

MYC

V-Myc Myelocytomatosis Viral Oncogene Homolog

Oncogene

CDC25A

Cell Division Cycle 25A

Oncogene

PIK3CA

Phosphatidylinositol-4, 5-Bisphosphate 3-Kinase

Oncogene

NOTCH3

Notch 3

Oncogene

EIF5A2

Eukaryotic Translation Initiation Factor 5A2

Oncogene

STAT3

Signal Transducer And Activator Of Transcription 3

Oncogene

ETV6

Ets Variant 6

Oncogene

EGFR

Epidermal Growth Factor Receptor

Oncogene

FGF1

Fibroblast Factor 1

Oncogene

AKT2

V-Akt Murine Thymoma Viral Oncogene Homolog 2

Oncogene

KRAS

V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog

Oncogene

RAB25

RAB25, Member RAS Oncogene Family

Oncogene

AURKA

Aurora Kinase A

Oncogene

PIK3R1

Phosphoinositide-3-Kinase, Regulatory Subunit 1

Oncogene

ERG

V-Ets Erythroblastosis Virus E26 Oncogene Homolog

Oncogene

ATAD2

ATPase Family, AAA Domain Containing 2

Oncogene

PDGFRA

Platelet-Derived Growth Factor Receptor, Alpha Polypeptide

Oncogene

ERBB2

V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2

  1. Presented in the table are the symbol and name of 36 tumor suppressors and oncogenes reported in the literature [2].