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Table 2 Clinical data sets used for modelling: we present disease, chemotherapy protocol and corresponding G-CSF schedules

From: Modelling chemotherapy effects on granulopoiesis

  G-CSF derivative Administration Disease Chemotherapy Reference
01 Filgrastim 5 μg/kg, days 2-13 Breast cancer TA [32]
02 Filgrastim 5 μg/kg, days 2-6 NSCLC CP [33]
03 Filgrastim 480 μg/kg, days 6-13 NHL high-CHOEP-14* [34]
04 Pegfilgrastim 30 μg/kg, day 2 Breast cancer TA [32]
05 Pegfilgrastim 60 μg/kg, day 2 Breast cancer TA [32]
06 Pegfilgrastim 100 μg/kg, day 2 Breast cancer TA [32]
07 Pegfilgrastim 6000 μg/kg, day 2 Breast cancer TA [35]
08 Pegfilgrastim 6000 μg/kg, day 2 Breast cancer TA [36]
09 Pegfilgrastim 30 μg/kg, day 2 NSCLC CP [33]
10 Pegfilgrastim 100 μg/kg, day 2 NSCLC CP [33]
11 Pegfilgrastim 300 μg/kg, day 2 NSCLC CP [33]
12 Pegfilgrastim 6000 μg/kg, day 2 NHL CHOP-14 [37]
13 Pegfilgrastim 6000 μg/kg, day 2 DLBCL R CHOP-14 [38]
14 - - NHL CHOP-21* (young) [39]
15 - - NHL CHOP-21* (elderly) [40]
16 - - NHL CHOEP-21* (young) [39]
17 - - NHL CHOEP-21* (elderly) [40]
18 - - HD BEACOPP-21* [41]
19 - - Breast cancer EC-T* [42]
20 Filgrastim 480 μg/kg, days 4-13 NHL CHOP-14* (young) [39]
21 Filgrastim 480 μg/kg, days 4-13 NHL CHOP-14* (elderly) [40]
22 Filgrastim 480 μg/kg, days 6-12 NHL CHOP-14* [43]
23 Filgrastim 480 μg/kg, days 4-13 NHL CHOEP-14* (young) [39]
24 Filgrastim 480 μg/kg, days 4-13 NHL CHOEP-14* (elderly) [40]
25 Filgrastim 480 μg/kg, days 6-13 NHL high-CHOEP-21* [43]
26 Filgrastim 480 μg/kg, days 8-13 HD BEACOPP-14* [44]
27 Filgrastim 480 μg/kg, days 8-15 HD BEACOPP-21 escalated* [41]
28 Filgrastim 480 μg/kg, days 3-10 Breast cancer E-T-C* [42]
29 Filgrastim 5 μg/kg, days 5-16 relapsed or persistent HD or NHL ESHAP [45]
30 Pegfilgrastim 6000 μg/kg, day 2 NHL CHOP-14* [46]
31 Pegfilgrastim 6000 μg/kg, day 4 NHL CHOP-14* [46]
32 Pegfilgrastim 100 μg/kg, day 6 relapsed or persistent HD or NHL ESHAP [45]
33 Pegfilgrastim 6000 μg/kg, day 2 DLBCL R CHOP-14 [47]
  1. Scenarios with access to raw data are denoted with*.