Table 2 Classification of cardiovascular targets
From: Insights from systems pharmacology into cardiovascular drug discovery and therapy
Target class | Numbers | Target child class | Numbers |
|---|---|---|---|
Receptor | 68 | GPCR | 52 |
| Â | Â | Nuclear Receptor | 9 |
| Â | Â | Other Receptor | 7 |
Transporter | 65 | Ion Channel | 53 |
| Â | Â | Solute Carrier | 8 |
| Â | Â | Other Transporter | 4 |
Enzyme | 55 | EC1 | 12 |
| Â | Â | EC2 | 6 |
| Â | Â | EC3 | 30 |
| Â | Â | EC4 | 6 |
| Â | Â | EC5 | 1 |
Other | 27 | Cytokine | 15 |
| Â | Â | Integrins | 3 |
| Â | Â | Annexin | 2 |
| Â | Â | Calmodulin | 2 |
| Â | Â | Antifibrotic Factor | 1 |
| Â | Â | Calnexin | 1 |
| Â | Â | Calreticulin | 1 |
| Â | Â | Fibrinogen | 1 |
| Â | Â | Transcription Factor | 1 |