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Table 2 Classification of cardiovascular targets

From: Insights from systems pharmacology into cardiovascular drug discovery and therapy

Target class Numbers Target child class Numbers
Receptor 68 GPCR 52
   Nuclear Receptor 9
   Other Receptor 7
Transporter 65 Ion Channel 53
   Solute Carrier 8
   Other Transporter 4
Enzyme 55 EC1 12
   EC2 6
   EC3 30
   EC4 6
   EC5 1
Other 27 Cytokine 15
   Integrins 3
   Annexin 2
   Calmodulin 2
   Antifibrotic Factor 1
   Calnexin 1
   Calreticulin 1
   Fibrinogen 1
   Transcription Factor 1