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Figure 2 | BMC Systems Biology

Figure 2

From: Positive regulation of Rho GTPase activity by RhoGDIs as a result of their direct interaction with GAPs

Figure 2

Free (non-GTPase-complexed) GDI concentration affects the prolongation of Rho activation in the GDI-integrated model. Rho activation dynamics were simulated at various concentration of free GDI. A) 600 min after stimulation in the canonical model. B) 600 min after stimulation in the GDI-integrated model. C) 1,800 min after stimulation in the GDI-integrated model. The activation levels of GTPases were expressed as the concentration of GTP-Rho/Effector complex.

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BMC Systems Biology

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