Figure 2

Comparison of pathway enrichment for Efficient Pairs detected by the two methods. The Efficient Pairs (EPs) were identified by the SIG++ method and by the Permutation method, respectively, and the pathway enrichment analysis for the involved targets are illustrated in the sub-figures (a ~ d). (a) EPs with regulation existent in normal and nonexistent in CIN I; (b) EPs with regulation nonexistent in normal and existent in CIN I; (c) EPs with regulation existent in CIN I and nonexistent in CIN III; (d) EPs with regulation nonexistent in CIN I and existent in CIN III. In each sub-figure, Pathway Enrichment Score = −lgP, where P refers to the enrichment significance of a biological process.