Regulation in stage 1
|
Regulation in stage 2
|
miRNA change
|
mRNA change
|
Relationship definition
|
Pair definition
|
|---|
Exist | Not exist | ↘ | ↗ | Agreement | Agreement Pair (AP) |
Exist | Not exist | ↗ | ↘ | Disagreement | — |
Exist | Not exist | - | ↗ | — | Typical Pair (TP) |
Not exist | Exist | ↗ | ↘ | Agreement | Agreement Pair (AP) |
Not exist | Exist | ↘ | ↗ | Disagreement | — |
Not exist | Exist | - | ↘ | — | Typical Pair (TP) |
- In this table, for a miRNA — mRNA pair, its regulation change, miRNA expression change and mRNA expression change between stage 1 (earlier stage) and stage 2 (later stage) are listed, thereupon the accordance between regulation change and expression change is defined. ‘miRNA change’ or ‘mRNA change’: the expression change of miRNA or mRNA; ‘↗’ or ‘↘’ : the expression was upregulated or downregulated in stage 2 compared with stage 1; ‘-’: the expression has no obvious change between two stages. ’Agreement’ or ‘Disagreement’: for a miRNA — mRNA pair, its regulation change and expression change is in agreement or in disagreement. The ‘Agreement Pair’ (AP) and ‘Typical Pair’ (TP) are collectively termed ‘Efficient Pair’ (EP).
