Skip to main content

Table 1 Definition of the accordance between regulation change and expression change for a miRNA — mRNA pair

From: microRNAs’ differential regulations mediate the progress of Human Papillomavirus (HPV)-induced Cervical Intraepithelial Neoplasia (CIN)

Regulation in stage 1 Regulation in stage 2 miRNA change mRNA change Relationship definition Pair definition
Exist Not exist Agreement Agreement Pair (AP)
Exist Not exist Disagreement
Exist Not exist - Typical Pair (TP)
Not exist Exist Agreement Agreement Pair (AP)
Not exist Exist Disagreement
Not exist Exist - Typical Pair (TP)
  1. In this table, for a miRNA — mRNA pair, its regulation change, miRNA expression change and mRNA expression change between stage 1 (earlier stage) and stage 2 (later stage) are listed, thereupon the accordance between regulation change and expression change is defined. ‘miRNA change’ or ‘mRNA change’: the expression change of miRNA or mRNA; ‘’ or ‘’ : the expression was upregulated or downregulated in stage 2 compared with stage 1; ‘-’: the expression has no obvious change between two stages. ’Agreement’ or ‘Disagreement’: for a miRNA — mRNA pair, its regulation change and expression change is in agreement or in disagreement. The ‘Agreement Pair’ (AP) and ‘Typical Pair’ (TP) are collectively termed ‘Efficient Pair’ (EP).