Figure 6
From: A computational model of PKD and CERT interactions at the trans-Golgi network of mammalian cells
Model responses to perturbation of PKD and CERT-mediated ceramide transport. (A) The influence of CERT mediated ceramide transfer on PKD activation is set to zero in the model. Expected PKD activation drops by less than 1 percent. (B) Ceramide transfer is increased by 10 % in the model. Expected PKD activity increases by 0.1%. (C) PKD activity is increased by 10% in the model. Expected ceramide transfer increases by 6%.