Genomic data assimilation using a higher moment filtering technique for restoration of gene regulatory networks

BMC Systems Biology

Table 3 The comparison results using the original model given by G1DBN and the five time-courses generated from a yeast-cell cycle network with Gaussian system noise of mean 0 and variance 0.01

	PR	RR	F-measure	TP	FP	TN	FN
HMEnPF	0.759	0.700	0.727	18.2	5.8	58.2	7.8
UKF	0.707	0.692	0.698	18.0	7.6	56.4	8.0
G1DBN	0.574	0.562	0.555	14.6	12.8	51.2	11.4

The comparison results of the proposed algorithm, the previous algorithm using UKF only [36], and G1DBN for the five time-courses generated from a yeast cell-cycle network with Gaussian system noise of mean 0 and variance 0.01. The results of ‘PR’, ‘RR’, ‘F-measure’, ‘TP’, ‘FP’, ‘TN’ and ‘FN’ for the five time-courses were averaged. The networks inferred by G1DBN were used as the original networks for the former two algorithms.

ISSN: 1752-0509