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Figure 3 | BMC Systems Biology

Figure 3

From: Effects of promoter leakage on dynamics of gene expression

Figure 3

Effects of promoter leakage on distribution. (A) no feedback (f = 0): the gene product distribution changes from bimodality to unimodality when the leakage rate increases. The parameter values are set as λ 1 = 40, γ 0 = 0.1, γ 1 = 0.2; (B) negative feedback: only one peak closed to the origin gradually becomes another peak away from the origin with the increase of the leakage rate. Other parameter values are set as λ 1 = 40, γ 0 = 0.1, γ 1 = 0.2, f = 0.1; (C) positive feedback: two peaks gradually become one peak away from the origin with the increase of the leakage rate, where the parameter values are set as λ 0 = 40, γ 0 = 0.1, γ 1 = 0.5, f = 0.1.

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