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Figure 8 | BMC Systems Biology

Figure 8

From: Robust network structure of the Sln1-Ypd1-Ssk1 three-component phospho-relay prevents unintended activation of the HOG MAPK pathway in Saccharomyces cerevisiae

Figure 8

Growth defects following Sln1 overexpression are not completely due to HOG pathway activation. A We assayed growth in wild-type and ssk1 Δ strains overexpressing Sln1 in response to β-estradiol or carrying an empty P G A L1 vector control. Deletion of Ssk1, which prevented HOG pathway activation by Sln1, partially alleviated the growth defect due to Sln1 overexpression. B Growth of cells on plates containing 10 μM β-estradiol indicated that ssk1 Δ reduced the toxicity of Sln1 overexpression.

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BMC Systems Biology

ISSN: 1752-0509

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