From: Iron acquisition and oxidative stress response in aspergillus fumigatus
Species | Type | Model states | |
---|---|---|---|
 |  | 0 | 1 |
hapX | Gene | Low expressed | High expressed |
sreA | Gene | Low expressed | High expressed |
HapX | Protein; bZip CCAAT-binding TF | Low active | High active |
SreA | Protein; GATA TF | Low active | High active |
RIA | Enzyme complex; reductive iron assimilation | Low active | High active |
EstB | Enzyme; TAFC-specific esterase | Low active | High active |
MirB | Protein; TAFC-specific importer | Low active | High active |
SidA | Enzyme; ornithine monooxygenase | Low active | High active |
TAFC | Extracellular siderophore | Low synthesized | High synthesized |
ICP | Iron consuming pathways | Low active | high active |
LIP | Labile iron pool | Low iron | High iron |
CccA | Protein; iron importer to vacuole | Low active | High active |
FC +Fe | Intracellular siderophore w/ bound iron | Low iron | High iron |
FC −Fe | Intracellular siderophore w/o bound iron | Low synthesized | High synthesized |
VAC | Vacuole | Low iron | High iron |
ROS | Reactive oxygen species | Low ROS | High ROS |
Yap1 | Protein; bZip TF | Low active | High active |
SOD2/3 | Enzyme; superoxide dismutase | Low active | High active |
Cat1/2 | Enzymes; hyphal catalases | Low active | High active |
Thioredoxin P. | Enzyme pathway | Low active | High active |
Iron | Physiological state | Low iron | High iron |
Superoxide | Physiological state | Low superoxide | High superoxide |