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Table 1 Positive feedback loops

From: Finding the positive feedback loops underlying multi-stationarity

N Motif Frequency
2 (−,−,−,−) 23/112 = 0.21
  (+,+,+,+) 35/112 = 0.31
3 (+,−,+,−,−,−) 19/108 = 0.18
  (+,+,+,+,+,+) 18/108 = 0.17
4 (+,+,−,+,−,+,−,−) 15/68 = 0.22
  (+,+,+,+,−,+,−,+) 15/68 = 0.22
  (+,+,+,+,+,+,+,+) 14/68 = 0.21
5 (+,+,+,+,+,+,−,+,−,+) 9/25 = 0.36
  (+,+,+,+,+,+,+,+,+,+) 7/25 = 0.28
6 (+,+,+,+,+,+,+,+,−,+,−,+) 6/28 = 0.21
  (+,+,+,+,+,+,+,+,+,+,+,+) 7/28 = 0.25
7 (+,+,+,+,+,+,+,+,+,+,−,+,−,+) 14/41 = 0.34
  1. For N=2, …,7 species nodes, the most frequent (>15%) positive feedback loops for each N are shown, together with their frequencies. At most four negative labels occur. Each cycle starts at a reaction node and the odd (even) labels correspond to reaction (species) nodes. Note that, for example, (-,-,+,+,+,+) and (+,+,-,-,+,+) are the same as they are permutations of each other.