Table 4 Overlapping genes for networks of nicotine, alcohol and opioid addiction; focus genes from literature are bolded

NFkB (complex)

112/86

ERK1/2

74/76

ERK1/2

74/62/76

ERK1/2

74/62

ARRB2

8/3

DRD2

6/3/4

IL1R1

7/4

DRD2

6/4

TAP1

5/5/3

IL1

6/8

HSPD1

5/4

SAA

4/3/4

DEFB4A/DEFB4B

6/4

TAP1

5/3

PSMB9

4/3/3

DRD2

6/3

SAA

4/4

TAPBP

4/3/3

ELANE

5/6

PSMB9

4/3

ELF3

4/3/2

F2RL1

5/6

TAPBP

4/3

TAC1

4/3/2

TAP1

5/5

ELF3

4/2

CLEC11A

3/4/2

F2R

5/3

TAC1

4/2

SMPD2

3/3/3

ADRBK1

5/2

PSMB10

3/3

CXCL3

3/3/2

Ikb

4/4

SMPD2

3/3

P2RY6

3/3/2

CXCL2

4/3

AKAP13

3/2

PSMB10

3/2/3

ELF3

4/3

CLEC11A

3/2

AKAP13

3/2/2

FPR2

4/3

CXCL3

3/2

TLR6

3/2/2

PSMB9

4/3

P2RY6

3/2

CRHR1

2/4/3

SAA

4/3

TLR6

3/2

CD244

2/3/3

TAC1

4/3

CD244

2/3

CXCL5

2/3/2

TAPBP

4/3

CRHR1

2/3

CCL21

2/2/2

DEFB103A/DEFB103B

4/2

CCL21

2/2

GMFG

2/2/2

LTF

3/5

CNR1

2/2

TNFSF11

3/5

CXCL5

2/2

TNFSF15

3/5

GMFG

2/2

CLEC11A

3/4

GPRASP1

2/2

TLR1

3/4

BDNF

2/1

CXCL3

3/3

KLF6

3/3

P2RY6

3/3

SMPD2

3/3

AKAP13

3/2

ARF6

3/2

IER3

3/2

PSMB10

3/2

TLR6

3/2

TRPC6

3/2

CRHR1

2/4

CCL22

2/3

CD244

2/3

CXCL5

2/3

CC2D1A

2/2

CCL21

2/2

GMFG

2/2

SH3GLB2

2/2

STAB2

2/2

TSC22D3

2/2

OPRM1

1/2