Fig. 5
From: Distinguishing the rates of gene activation from phenotypic variations
The mean switching time (MST) as a function of κ with different positive feedback strength. a MST curve of off-to-on switch. b MST curve of on-to-off switch. Parameters are the same with with Fig. 2 except d G , k G , k G0, and K. When κ changes, d G should change simultaneously to keep d G /k G , d G /k G0 locked (these ratios are the same with Fig. 2). We use different strength of positive feedback for simulations, which is K=2754 (green dashed lines with square markers), 3000 (black solid lines), 3211 (red dashed lines with triangular markers). All of the results are obtained from Gillespie’s algorithm