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Fig. 12 | BMC Systems Biology

Fig. 12

From: Validation and selection of ODE based systems biology models: how to arrive at more reliable decisions

Fig. 12

Percentage prediction errors (PE) of the true model structure in scenario 2. Each box plot shows the distribution of PE over 100 different realizations of the data. The red dots indicate the outliers which lie outside approximately 99.3 % coverage if the data is normally distributed. Gray and yellow boxes refer to the lowest and the highest dose schemes, respectively. Each row in the figure corresponds to a single scheme. The labels on the x-axis show the specific dose and the cell type of the data on which the validation was performed. The labels indicate also the medians of the PE distribution summarized visually by the box plots. In each graph, the ten realizations with the highest PE are located above the black dashed line. The region above this line is compressed for visual ease. a PE obtained on Sln1 validation subsets in the lowest dose scheme. b PE obtained on Sho1 validation subsets in the lowest dose scheme. c PE obtained on WT validation subsets in the lowest dose scheme. d PE obtained on Sln1 validation subsets in the highest dose scheme. e PE obtained on Sho1 validation subsets in the highest dose scheme. f PE obtained on WT validation subsets in the highest dose scheme

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