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Table 3 List of PathExpand interactors

From: The gastrin and cholecystokinin receptors mediated signaling network: a scaffold for data analysis and new hypotheses on regulatory mechanisms

CCK model protein interactors

Protein name

Annotated in pathway databasesa

AFAP1

actin filament associated protein 1

 

AKAP14

A kinase (PRKA) anchor protein 14

 

ARHGAP31

Rho GTPase activating protein 31

Yes

ARHGEF25

Rho guanine nucleotide exchange factor (GEF) 25

 

ASXL1

additional sex combs like 1 (Drosophila)

 

ATP5J

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6

Yes

BLVRA

biliverdin reductase A

Yes

BNIP1

BCL2/adenovirus E1B 19 kDa interacting protein 1

Yes

CCDC88A

coiled-coil domain containing 88A

 

CD59

CD59 molecule, complement regulatory protein

Yes

CPS1

carbamoyl-phosphate synthase 1, mitochondrial

Yes

DDR2

discoidin domain receptor tyrosine kinase 2

 

DUSP2

dual specificity phosphatase 2

Yes

DUSP22

dual specificity phosphatase 22

Yes

DUSP4

dual specificity phosphatase 4

Yes

DUSP5

dual specificity phosphatase 5

Yes

DUSP7

dual specificity phosphatase 7

Yes

DUSP9

dual specificity phosphatase 9

Yes

EIF4EBP2

eukaryotic translation initiation factor 4E binding protein 2

 

EIF4EBP3

eukaryotic translation initiation factor 4E binding protein 3

 

ERRFI1

ERBB receptor feedback inhibitor 1

 

FAM59A

family with sequence similarity 59, member A

 

FCGR2C

Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)

Yes

FKBP1A

FK506 binding protein 1A, 12 kDa

 

FLT4

fms-related tyrosine kinase 4

Yes

GAB3

GRB2-associated binding protein 3

Yes

GJB1

gap junction protein, beta 1, 32 kDa

Yes

GLTSCR1

glioma tumor suppressor candidate region gene 1

 

GNB1L

guanine nucleotide binding protein (G protein), beta polypeptide 1-like

 

GUCY1A3

guanylate cyclase 1, soluble, alpha 3

Yes

ICMT

isoprenylcysteine carboxyl methyltransferase

 

IQGAP2

IQ motif containing GTPase activating protein 2

 

IRF5

interferon regulatory factor 5

Yes

ITPKA

inositol-trisphosphate 3-kinase A

Yes

KIAA2026

KIAA2026

 

KSR1

kinase suppressor of ras 1

 

MAPK15

mitogen-activated protein kinase 15

Yes

MCF2L

MCF.2 cell line derived transforming sequence-like

Yes

MTPN

myotrophin

 

MUC12

mucin 12, cell surface associated

 

NCF1B

neutrophil cytosolic factor 1B pseudogene

 

NFATC3

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

Yes

NFKBIZ

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta

 

OGN

osteoglycin

 

OPHN1

oligophrenin 1

Yes

PARD6G

par-6 partitioning defective 6 homolog gamma (C. elegans)

Yes

PDCD11

programmed cell death 11

 

PDE3B

phosphodiesterase 3B, cGMP-inhibited

Yes

PEBP4

phosphatidylethanolamine-binding protein 4

Yes

PFKFB3

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

Yes

PHLPP1

PH domain and leucine rich repeat protein phosphatase 1

Yes

PI4K2B

phosphatidylinositol 4-kinase type 2 beta

 

PIK3C2B

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta

Yes

PLEKHG2

pleckstrin homology domain containing, family G (with RhoGef domain) member 2

Yes

PPP1R14A

protein phosphatase 1, regulatory (inhibitor) subunit 14A

Yes

PTPN7

protein tyrosine phosphatase, non-receptor type 7

Yes

PTPRR

protein tyrosine phosphatase, receptor type, R

Yes

RASGRP3

RAS guanyl releasing protein 3 (calcium and DAG-regulated)

Yes

RET

ret proto-oncogene

Yes

RIPK4

receptor-interacting serine-threonine kinase 4

 

RPL27

ribosomal protein L27

Yes

RPS6KA4

ribosomal protein S6 kinase, 90 kDa, polypeptide 4

Yes

SEMG2

semenogelin II

 

SH2D3C

SH2 domain containing 3C

 

SIT1

signaling threshold regulating transmembrane adaptor 1

 

TBC1D3F

TBC1 domain family, member 3 F

 

TIAF1

TGFB1-induced anti-apoptotic factor 1

 

TNP1

transition protein 1 (during histone to protamine replacement)

 

TPX2

TPX2, microtubule-associated, homolog (Xenopus laevis)

Yes

TRH

thyrotropin-releasing hormone

 
  1. aincludes KEGG, PANTHER, Biocarta and Reactome