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Table 2 Ranges of the uniform proposal distribution used for parameter sampling. Kinetic rate parameters were sampled using a uniform proposal distribution with ranges as depicted in the table. Physiologically meaningful boundaries were chosen if no specific information was available from previous studies (last three rows). In the case where the parameter distribution was post-hoc trimmed, the effective range is shown and the original sampling range is given in brackets

From: Logical-continuous modelling of post-translationally regulated bistability of curli fiber expression in Escherichia coli

Parameter names

Unit

Lower bound

Upper bound

References

\(K_{\text {m}}^{\text {YhjH}}\)

molecules

100

3000

[35, 49]

\(K_{\text {m}}^{\text {YciR}}\)

molecules

100

1000 (3000)

[50] p. 103, [35]

\(K_{\text {d}}^{\text {YciR}}\)

molecules

100

3000

[50] p. 103, [35]

\(K_{\text {i}}^{\text {YegE}}\)

molecules

0

2000

[37]

V max1, V max2, k YdaMact, k YciRact

molecules /s

0

2000

[49, 51]

\(K_{\text {d}}^{\text {YdaM}}\)

molecules

100

3000

physiol. range

YciRtot, YdaMtot, \(K_{\text {d}_{\text {polymer}}}^{\text {YdaM}} \)

molecules

0

2000

physiol. range

k YciRde, k YdaMde

molecules /s

0

2000

physiol. range