Fig. 8From: Complex regulation of Hsf1-Skn7 activities by the catalytic subunits of PKA in Saccharomyces cerevisiae: experimental and computational evidencesSingle-cell predictions of the temporal dynamics for Bcy1, cAMP, HSE-lacZ, and Tpk3 in WT and three mutants. Temporal dynamics for four selected nodes: Bcy1 (a), cAMP (b), HSE-lacZ (c), and Tpk3 (d). Line colors correspond to different strains. Simulations were made starting from a random initial condition for each strain. Expression and time are given in arbitrary units. Background color represents the temperature of the culture: 25 °C (blue) and 39 °C (pink)Back to article page