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Table 2 Optimized model parameters

From: Regulation of ERK-MAPK signaling in human epidermis

Species

Baseline level (b)

Amplitude (a)

Tissue Ca2+ (Ca)

0.754

0.092

Plasma membrane CaM (CaM)

0.363

0.485

  1. Baseline level (b) and amplitude (a) parameters for the Ca2+ and plasma-membrane CaM fractional activations were optimized to produce the closest least-squares fit to the cytoplasmic and nuclear phospho-ERK-1/2 immunofluorescence data (for all three patients)