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Fig. 5 | BMC Systems Biology

Fig. 5

From: A correction method for systematic error in 1H-NMR time-course data validated through stochastic cell culture simulation

Fig. 5

Correction applied to example data. a White points represent initially observed concentrations that were marked for correction by the algorithm, while black points represent final compound concentrations (with arrows signifying correction). Smoothing lines were generated using the gam-5 model using uncorrected (solid line) and corrected (dashed line) data. Time-course data was collected as described in the Cell culture subsection of the Methods section. b Derivatives calculated from the uncorrected (solid line) and corrected (dashed line) smoothed fits

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