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Fig. 6 | BMC Systems Biology

Fig. 6

From: A correction method for systematic error in 1H-NMR time-course data validated through stochastic cell culture simulation

Fig. 6

Average bias as a function of smoothing model. Lines represent averages of simulated median relative deviations from smoothing fits. Dashed lines are used to distinguish timepoints simulated with a 5 % bias. The gam-6/loess-0.5 models correspond to a greater degree of smoothing in comparison to gam-3/loess-2.0. The number of observations corresponds to the number of timepoints in the generated metabolic trends. Although the number of compounds per time-course set was varied in the simulation, these were found to have no impact on average trends

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