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Table 1 Parameter ranges used in the trend shape simulation of reference data (via Eqs. 1-3). Parameter values were drawn from a uniform distribution constrained to the given ranges. Where two ranges are given, the range was chosen randomly for each trend based on the given probability

From: A correction method for systematic error in 1H-NMR time-course data validated through stochastic cell culture simulation

Trend Parameter Range 1 Range 2 P(Range 1)
Sigmoidal decrease a 0.200–0.600 0.600–0.900 0.05
  b 0.100–0.180 NA 1.00
Sigmoidal increase a 0.045–0.055 0.945–0.955 0.15
  b 0.200–0.400 0.100–0.300 0.15
Concave a 3.500–4.500 NA 1.00
  b 2.500–3.500 NA 1.00
  c 0.000–0.200 NA 1.00
  d 0.800–0.900 NA 1.00