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Table 2 The nonlinear correlation coefficient of OTU pairs, predicted by RMN algorithm as co-regulated triplets, under different level of noise interference. A triplet predicted by RMN algorithm is composed of cooperator, competitor and target. Here L0.8 represents for 0≦ L d( O m , O c , O t ) ≦0.8 and D0.8 represents for D(O m , O c , O t ) < 0.8

From: Inferring microbial interaction network from microbiome data using RMN algorithm

Non-noise

O m O t_count

O c O t_count

Total_count

Pr value (%)

L0.8D0.8

3

3

26

23.1

L1.8D0.8

4

0

24

16.7

L2.8D0.8

7

5

24

50.0

L3.8D0.8

6

1

22

31.8

L0.8D1.8

2

2

24

16.7

L0.8D2.8

1

2

24

12.5

L0.8D3.8

1

1

24

8.3

Low-noise

O m O t_count

O c O t_count

Total_count

Pr value (%)

L0.8D0.8

3

1

26

15.4

L1.8D0.8

6

2

22

36.4

L2.8D0.8

5

0

22

22.7

L3.8D0.8

1

4

24

20.8

L0.8D1.8

4

2

24

25.0

L0.8D2.8

1

0

24

4.2

L0.8D3.8

3

1

24

16.7

Medium-noise

O m O t_count

O c O t_count

Total_count

Pr value (%)

L0.8D0.8

5

2

24

29.2

L1.8D0.8

5

3

22

36.4

L2.8D0.8

5

1

22

27.3

L3.8D0.8

7

1

22

36.4

L0.8D1.8

4

1

24

20.8

L0.8D2.8

2

1

24

12.5

L0.8D3.8

4

2

26

23.1

High-noise

O m O t_count

O c O t_count

Total_count

Pr value (%)

L0.8D0.8

3

3

24

25.0

L1.8D0.8

6

5

22

50.0

L2.8D0.8

7

4

22

50.0

L3.8D0.8

5

0

20

25.0

L0.8D1.8

3

2

24

20.8

L0.8D2.8

2

1

24

12.5

L0.8D3.8

2

2

24

16.7