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Fig. 3 | BMC Systems Biology

Fig. 3

From: Clustering reveals limits of parameter identifiability in multi-parameter models of biochemical dynamics

Fig. 3

The NF κB signalling pathway. a Schematic representation of the reactions involved. b Clustering of the model parameters reveals that parameters which characterise modules close in the network topology are generally more correlated than those far apart. Sensitivity vectors were calculated for a specific TNF- α stimulation to reflect physiological conditions (increase, plateau, decrease): see Figure 6B in Additional file 1

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