Table 1 Parameter set used for simulations of the cell differentiation model, as suggested in Ref. [29]

*

β

2

Hill coefficient

Progenitor, (P)

a _p

0.2

Auto-activation

b _p

0.5

Basal activity

m _p

{8, 10}

Inflection point

c _pp

0.1

Self-inhibition strength

c _op , c _cp

0.5

Inhibition strength on x _o ,x _c

k _p

0.1

Decay rate

Osteoblast and Chrondrocyte, (O,C)

a _o , a _c

0.1

Autoactivation

b _o , b _c

1

Basal activity

m _o , m _c

1

Inflection point

c _oo , c _cc

0.1

Self-inhibition strength

c _oc , c _co

0.1

Mutual inhibition strength

k _o , k _c

0.1

Decay rate