Fig. 9From: Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potentialExamples of CNAs regulatory network. a) Deletions of miR-335 produces effect that appear as promoting migration, invasion, and metastasis. In particular, it has been shown to be an important negative regulator of SOX4, and TENASCIN-C b) Amplifications of miR-33 produce effects that appear as dyseregulation of PTEN pathwayBack to article page