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Table 1 Genes mutated and their alterations in BC

From: Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential

Genes Genetic alterations References
MYC Amplifications and translocations [2529]
CCND1 Amplifications and Translocations [30]
HER2 Amplifications [1518]
TOP2A Amplifications or Deletions [22, 23]
PIK3CA, MET Amplifications [24]
PNRC1 Deletions [15]
DBC1 and DEC1 Amplifications or Deletions [15]
TSPAN1 Deletions [33]
EGFR Amplifications [19, 20]
ESR1 Amplifications [32]
EMSY Amplifications [34]