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Table 10 miRNA deregulated by integration miRNA and mRNA

From: Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential

Biomarker

Biological effect

References

miR-16, 155, 125b, 374a

predictive of overall survival (P = 0.05)

[307]

miR-16, 125b, 374a, 374b, 421, 655, 497

predictive of distant-disease free survival (P = 0.009)

[307]

miR-1307, 103, 328, 83, 874, 484, 148b

associated with overall survival across different clinical and molecular subclasses

[308]

miR-767-3p, 128a, 769–3, 135a, and miR-27b, 144, 210, 42, 150, 30c

associated with DRFS in estrogen receptor

[309]

miR-335, 337-5p, 451, 486-3p, 520a-5p, 548d-5p, 15a, 24, 29a, 30b, 320, 342-5p, 342-3p

associated with inflammatory breast cancer

[310]

miR-150, 155, 142

have strong positive correlation to the immune response module

[311]

miR-130b, 19a, 449a, 299, 154, 145

association with proliferation

[311]

miR-29c

associated with cell adhesion/extra cellular matrix

[311]

miR-125b, miR-182 and miR-183

highly overexpressed in ductal carcinoma in situ

[312]

miR-200c, miR-205, and miR-375

down-regulated miRNAs in invasive cell lines

[313]