Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential

Table 11 Example of network between miRNA and their targets in BC

miRNA	Targets	Phenotype	Ref.
miR-21	BCL-2,PTEN, PDCD4,TPM1, maspin	Migration, invasion	[318, 319]
miR-335	SOX4, Tenascin-C	Migration, invasion	[326–328]
miR-10b	HOXD10, RhoC	Migration, invasion	[320, 321]
let-7	H-RAS, HMGA2, LIN28, PEBP1	Proliferation, differentiation	[322, 323]
miR-200	BMI2, ZEB1, ZEB2, Sec-23a	Migration	[324]

ISSN: 1752-0509