Table 4 miRNAs deregulated in BC
MiRNAs | Biological effect | References |
|---|---|---|
miR-200 | It associated with the luminal subtype | Gregory et al. [132] |
miR-145 and miR-205 | It associated with basal like triple negative tumours | Sempere et al. [133] |
miR-125b | It can predict poor response to taxol-based treatment in vivo | Zhou et al. [134] |
miR-181a | It correlated with lymph node metastasis | Taylor et al. [135] |
miR-106b-25 | It can significantly predict a good relapse time | Smith et al. [136] |
miR-31 | It controls metastasis and increases the survival of patients | Valastyan et al. [147] |
let-7 | It suppressed metastasis | Yu et al. [159] |
miR-375 | It negatively regulate ER expression | de Souza et al. [137] |
miR-10b, miR-155 | They correlate with metastasis | Mar-Aguilar et al. [169] |
miR-21 | It associated with cell migration and invasion | Si et al. [168] |