Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential

Table 8 Two step approaches to quantify gene dosage effect

Analysis	Type	References
- regression	• univariate linear	[279–282]
	• multivariate linear
	• nonlinear
- correlation	• signal-to-noise ratio	[283–288]
	• Pearson's correlation
	• Algorithm Array CGH Expression integration tool (ACE-it)
	• discriminating score

ISSN: 1752-0509