Table 1 Kinetic isotope effects measured on five central metabolic enzymes. For multiply labeled isotopomers, α coefficients were approximated from KIEs of singly labeled isotopomers assuming KIEs are cumulative [28]; for instance, α ^PYR_110 _PDH  = α ^PYR_100 _PDH . α ^PYR_010 _PDH

From: Impact of kinetic isotope effects in isotopic studies of metabolic systems