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Table 2 Average c parameter estimates, relative standard errors and relative bias as a function of number of experiments for acetylornithine aminotransferase when σ v =0.2. Results are based on 1,000 simulated data sets. “n” is the number of experiments. “Avg Est” is the average value of the estimates. “Rel SE” is the relative standard error, and “Rel bias” is the relative bias

From: Towards in vivo estimation of reaction kinetics using high-throughput metabolomics data: a maximum likelihood approach

n Run time True Avg Est Rel SE Rel bias
12 1.74sec/simulation c 1:2.578 2.315 0.188 0.102
   c 2:3.733 3.68 0.108 0.014
   c 3:3.524 3.54 0.10 0.007
24 7.98sec/simulation c 1:2.578 2.567 0.143 0.004
   c 2:3.733 3.755 0.081 0.006
   c 3:3.524 3.544 0.087 0.006
30 20.04sec/simulation c 1:2.578 2.573 0.129 0.002
   c 2:3.733 3.742 0.062 0.002
   c 3:3.524 3.517 0.073 0.002