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Table 6 Comparison of the accuracy of prior methods: total least square (TLS), ordinary least square (OLS), direct linear plot (DLP), double reciprocal plot(DRP) and InVEst. True c 1=1.5, True c 2=0.8. Data have relative errors in all variables. Results are based on 1,000 simulated data sets of 30 experiments, each. “Avg Est” is the average value of the estimates. “Rel SE” is the relative standard error

From: Towards in vivo estimation of reaction kinetics using high-throughput metabolomics data: a maximum likelihood approach

  Avg Est c 1 Avg Est c 2 Rel SE c 1 Rel SE c 2
TLS 0.840 0.940 0.389 0.143
OLS 1.036 0.921 0.413 0.147
DLP 1.396 0.883 0.429 0.262
DRP 1.859 0.498 0.307 1.124
InVEst 1.518 0.766 0.128 0.112