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Fig. 2 | BMC Systems Biology

Fig. 2

From: Conditional robustness analysis for fragility discovery and target identification in biochemical networks and in cancer systems biology

Fig. 2

Problem formulation. The fragility problem in the oncology context is related to the cancer cells signaling network, and the goal is to reduce the cell proliferation attitude acting in few target molecules. The problem is related to the conditional robustness problem, namely the problem of shifting the probability density function of a proliferation signal in cancer cells toward the density describing the normal cells

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