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Fig. 2 | BMC Systems Biology

Fig. 2

From: The relationship between stochastic and deterministic quasi-steady state approximations

Fig. 2

The numerically estimated error of deterministic and stochastic QSSA show strong correlation. ab The error of the stochastic QSSA is closely corelated to the error in the deterministic QSSA when k f (a) and K D (b) change. Here, the error in the deterministic QSSA is measured using the relative differences in deterministic solutions R(t) given in Eq. 8. The error of the stochastic QSSA is measured using the relative difference of coefficient of variation at steady state between the full and the reduced model. Note that since the error of stochastic and deterministic QSSA were measured in different ways, they can potentially differ, even by orders of magnitude. See Additional file 1: Figure S2 for the difference of the distributions of R between the stochastic QSSA and full model. The error bars were estimated with the boot strap method as described in ‘Methods’. See Fig. 1 for the details of parameters

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