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Table 2 Summary of the case studies. Each column describes a calibration problem. Further details can be found in Additional file 3 (numerical data) and Additional file 4 (detailed descriptions including the model differential equations)

From: Robust and efficient parameter estimation in dynamic models of biological systems

Short name BBG FHN MAPK GOsc TGFB TSMP CHM
Description Biomass FitzHugh- MAPK Goodwin’s TGF- β 3-Step Chemotaxis
  Batch Nagumo Signalling Oscillator Signalling Metabolic Signalling
  Growth Oscillator Pathway   Pathway Pathway Pathway
Reference [123] [124, 125] [126] [127] [48] [44] [128]
Implementation of dynamics [123] BIOMD00000000010 BIOMD00000000346 , [129] [130] [48] [44] BIOMD00000000404
Total parameters 4 3 22 8 21 36 60
Estimated parameters 4 3 6 8 18 36 38
States 2 2 8 3 18 8 26
Observed states 2 1 2 3 16 8 7(+1)
Experiments 1 1 1 1 1 8 2
Data points 22 6 20 20 240 1344 160
  1. *The dynamic model can be found in the Biomodels Database (http://www.ebi.ac.uk/biomodels-main)